Doxycycline treatment of Brugia malayi-infected persons reduces microfilaremia and adverse reactions after diethylcarbamazine and albendazole treatment.
Identifieur interne : 006B46 ( Main/Exploration ); précédent : 006B45; suivant : 006B47Doxycycline treatment of Brugia malayi-infected persons reduces microfilaremia and adverse reactions after diethylcarbamazine and albendazole treatment.
Auteurs : Taniawati Supali [Indonésie] ; Yenny Djuardi ; Kenneth M. Pfarr ; Heri Wibowo ; Mark J. Taylor ; Achim Hoerauf ; Jeanine J. Houwing-Duistermaat ; M. Yazdanbakhsh ; Erliyani SartonoSource :
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [ 1537-6591 ] ; 2008.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Albendazole (effets indésirables), Albendazole (usage thérapeutique), Animaux, Association de médicaments, Brugia malayi (), Diéthylcarbamazine (effets indésirables), Diéthylcarbamazine (usage thérapeutique), Doxycycline (usage thérapeutique), Enfant, Femelle, Filaricides (effets indésirables), Filaricides (usage thérapeutique), Filariose lymphatique (traitement médicamenteux), Humains, Mâle, Méthode en double aveugle, Résultat thérapeutique, Sujet âgé.
- MESH :
- effets indésirables : Albendazole, Diéthylcarbamazine, Filaricides.
- traitement médicamenteux : Filariose lymphatique.
- usage thérapeutique : Albendazole, Diéthylcarbamazine, Doxycycline, Filaricides.
- Adolescent, Adulte, Adulte d'âge moyen, Animaux, Association de médicaments, Brugia malayi, Enfant, Femelle, Humains, Mâle, Méthode en double aveugle, Résultat thérapeutique, Sujet âgé.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Albendazole (adverse effects), Albendazole (therapeutic use), Animals, Brugia malayi (drug effects), Child, Diethylcarbamazine (adverse effects), Diethylcarbamazine (therapeutic use), Double-Blind Method, Doxycycline (therapeutic use), Drug Therapy, Combination, Elephantiasis, Filarial (drug therapy), Female, Filaricides (adverse effects), Filaricides (therapeutic use), Humans, Male, Middle Aged, Treatment Outcome.
- MESH :
- chemical , adverse effects : Albendazole, Diethylcarbamazine, Filaricides.
- chemical , therapeutic use : Albendazole, Diethylcarbamazine, Doxycycline, Filaricides.
- drug effects : Brugia malayi.
- drug therapy : Elephantiasis, Filarial.
- Adolescent, Adult, Aged, Animals, Child, Double-Blind Method, Drug Therapy, Combination, Female, Humans, Male, Middle Aged, Treatment Outcome.
Abstract
The efficacy of doxycycline for treating the causal agent of human lymphatic filariasis, Brugia malayi, is unknown. Standard treatment with diethylcarbamazine-albendazole is associated with adverse reactions. We assessed whether doxycycline alone or in combination with diethylcarbamazine-albendazole would lead to sustained amicrofilaremia and reduced incidence of adverse reactions.
DOI: 10.1086/586753
PubMed: 18419441
Affiliations:
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Le document en format XML
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Standard treatment with diethylcarbamazine-albendazole is associated with adverse reactions. We assessed whether doxycycline alone or in combination with diethylcarbamazine-albendazole would lead to sustained amicrofilaremia and reduced incidence of adverse reactions.</div></front></TEI><affiliations><list><country><li>Indonésie</li></country></list><tree><noCountry><name sortKey="Djuardi, Yenny" sort="Djuardi, Yenny" uniqKey="Djuardi Y" first="Yenny" last="Djuardi">Yenny Djuardi</name><name sortKey="Hoerauf, Achim" sort="Hoerauf, Achim" uniqKey="Hoerauf A" first="Achim" last="Hoerauf">Achim Hoerauf</name><name sortKey="Houwing Duistermaat, Jeanine J" sort="Houwing Duistermaat, Jeanine J" uniqKey="Houwing Duistermaat J" first="Jeanine J" last="Houwing-Duistermaat">Jeanine J. Houwing-Duistermaat</name><name sortKey="Pfarr, Kenneth M" sort="Pfarr, Kenneth M" uniqKey="Pfarr K" first="Kenneth M" last="Pfarr">Kenneth M. Pfarr</name><name sortKey="Sartono, Erliyani" sort="Sartono, Erliyani" uniqKey="Sartono E" first="Erliyani" last="Sartono">Erliyani Sartono</name><name sortKey="Taylor, Mark J" sort="Taylor, Mark J" uniqKey="Taylor M" first="Mark J" last="Taylor">Mark J. Taylor</name><name sortKey="Wibowo, Heri" sort="Wibowo, Heri" uniqKey="Wibowo H" first="Heri" last="Wibowo">Heri Wibowo</name><name sortKey="Yazdanbakhsh, M" sort="Yazdanbakhsh, M" uniqKey="Yazdanbakhsh M" first="M" last="Yazdanbakhsh">M. Yazdanbakhsh</name></noCountry><country name="Indonésie"><noRegion><name sortKey="Supali, Taniawati" sort="Supali, Taniawati" uniqKey="Supali T" first="Taniawati" last="Supali">Taniawati Supali</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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